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The kinetic research on diazepam metabolism in male Wistar rats exposed that extensive metabolizer rats experienced markedly greater V(max) and smaller sized K(m) in diazepam p-hydroxylation than All those of poor metabolizer rats, indicating the presence of substantial affinity substantial ability p-hydroxylase enzyme in intensive metabolizer rats
Diazepam is typically used intermittently to the prevention of febrile seizures that could occur in small children less than 5 years of age.[twenty] Recurrence rates are lessened, but side effects are prevalent and the decision to deal with febrile seizures (which are benign in nature) with medication uses these elements as A part of the analysis.D